How to live longer in 2 minutes – The science behind NMN and anti-aging

NMN (nicotinamide mononucleotide) the ‘fountain of youth’?

Renowned Harvard University geneticist David Sinclair recently made a startling assertion: Scientific data shows he has knocked more than 20 years off his biological age.

So what is the 50 year-old’s secret? He says his daily protocol includes ingesting a molecule his own research found improved health and lengthened the life span of yeast cells and mice – NMN

NMN (Nicotinamide mononucleotide) is a nucleotide that is most recognized for its role as an intermediate of nicotinamide adenine dinucleotide (NAD+) biosynthesis.

David Sinclair recently appeared on the popular podcast – The Joe Rogan Experience. David spoke about his study into longevity and anti-aging, as well as his new book “Lifespan – Why We Age, And Why We Don’t Have To”. 

Despite being 50 years of age, David looks a lot younger. Given that he is one of the worlds leading researches into anti-aging it is natural to ask – what’s his secret?

One thing David is fast to point out is that he’s a researcher – not a medical doctor. He does not give health recommendations or tell people what they should be doing. However, he was able to share what he himself takes on a daily basis.

David Sinclair’s Supplementation:

What do Resveratrol & NMN do in relation to living longer?

David says that NMN and resveratrol are critical for the function of the ‘sirtuin genes’. Sirtuins play a large role in DNA repair – a critical component to longer life. 

He describes resveratrol as the “accelerator pedal” for the sirtuin genes (increasing their activation), and NMN as the fuel. Without “fuel”, resveratrol won’t work. The reason that resveratrol won’t work effectively without NMN, is that sirtuin activation requires youthful NAD levels, but by 50 years old, we have about half the level of NAD we had in our 20s (NAD being a molecule that is essential to energy production in our cells).

So in effect, you take resveratrol to increase activation of the sirtuin genes, and NMN to ensure the sirtuins have enough energy to work properly.

So, what else is David doing to stay healthy?

David is an advocate of ‘intermittent fasting’. He skips breakfast and/or lunch whenever possible.

For more on NMN and Resveratrol, visit 

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